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    Week after Cyclone Amphan, Kolkata hit by squall at 96 kmph – india news

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    Maharashtra, Delhi, Tamil Nadu, Gujarat, Rajasthan, Uttar Pradesh, Bihar

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    India under Narendra Modi can’t be threatened: Ravi Shankar Prasad on China face-off | India News

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    Sari Baldauf Takes Over as Nokia Chair From Siilasmaa | Technology News

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    Crackdown on farm protests, Tikait holds out in UP Gate standoff | India News

    Week after Cyclone Amphan, Kolkata hit by squall at 96 kmph – india news

    Week after Cyclone Amphan, Kolkata hit by squall at 96 kmph – india news

    Maharashtra, Delhi, Tamil Nadu, Gujarat, Rajasthan, Uttar Pradesh, Bihar

    Maharashtra, Delhi, Tamil Nadu, Gujarat, Rajasthan, Uttar Pradesh, Bihar

    LAC stand-off | Trump surprises with offer to mediate as India, China stress bilateral resolution

    LAC stand-off | Trump surprises with offer to mediate as India, China stress bilateral resolution

    Air travel in India and the US: What has changed?

    Air travel in India and the US: What has changed?

    Mamata petitions PM against ‘whimsical’ scheduling of Shramik trains | India News

    Mamata petitions PM against ‘whimsical’ scheduling of Shramik trains | India News

    After Hard Position On New Map And Rebuke By India, A Change In Nepal

    After Hard Position On New Map And Rebuke By India, A Change In Nepal

    Lockdown: Toddler’s failed attempt to wake up dead mother leaves internet, conscience shaken | India News

    Lockdown: Toddler’s failed attempt to wake up dead mother leaves internet, conscience shaken | India News

    India under Narendra Modi can’t be threatened: Ravi Shankar Prasad on China face-off | India News

    India under Narendra Modi can’t be threatened: Ravi Shankar Prasad on China face-off | India News

  • World

    Philippines secures $900 mn in loans from World Bank, ADB for Covid-19 vaccines

    Crowds flock to city streets ahead of rule of six restrictions

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    Researchers to test dogs’ ability to sniff out coronavirus, World News

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    Mike Pompeo says Hong Kong no longer autonomous from China

    Mike Pompeo says Hong Kong no longer autonomous from China

    Wuhan Coronavirus: How Wuhan tested 6.5 million for coronavirus in days | World News

    Wuhan Coronavirus: How Wuhan tested 6.5 million for coronavirus in days | World News

    Exams Amid the Olives for Students in Coronavirus Italy | World News

    Exams Amid the Olives for Students in Coronavirus Italy | World News

    California sues makers of Criminal Minds over sexual misconduct | World news

  • Politics
    ‘Nothing More Than Desperate Case of Political Compulsion’, Punjab CM on SAD Snapping Ties With Oldest Ally BJP

    ‘Nothing More Than Desperate Case of Political Compulsion’, Punjab CM on SAD Snapping Ties With Oldest Ally BJP

    ‘Video games are a great place for politics’: meet India’s modern magical realists | Games

    Shinzo Abe’s resignation unlikely to hit India-Japan annual summit plans

    Popular Front of India (PFI) role in smuggling of gold not established yet

    Nehru : The Architect of Modern India

    Nehru : The Architect of Modern India

    Mamata seeks PM Modi’s intervention, urges Centre to not pursue politics in times of crisis

    Mamata seeks PM Modi’s intervention, urges Centre to not pursue politics in times of crisis

    Covid-19 lockdown: 179 stranded Pakistan nationals repatriated from India via Attari-Wagah Border – Economic Times

    Covid-19 lockdown: 179 stranded Pakistan nationals repatriated from India via Attari-Wagah Border – Economic Times

    Scindia ignored ideology as he feared for political future, will not get respect in BJP: Rahul

    Decades later, Nehru remains most hotly debated Indian politician ever

    AgustaWestland accused Michel questioned in Tihar, asked to name ‘prominent politicians’

    AgustaWestland accused Michel questioned in Tihar, asked to name ‘prominent politicians’

  • Business

    Telecoms set the business tone in Myanmar, Telecom News, ET Telecom

    Asian Shares Advance Following Upbeat US Jobs Report | Business News

    Lockdown diaries with Sanjiv Bajaj

    Boeing begins cutting workforce with 6,770 layoffs in US – business news

    Boeing begins cutting workforce with 6,770 layoffs in US – business news

    UCO Bank slashes lending rate by 40 basis points

    UCO Bank slashes lending rate by 40 basis points

    Stock Market: Live News During the Coronavirus Pandemic

    Stock Market: Live News During the Coronavirus Pandemic

    Patanjali to raise Rs 250 crore through debentures

    Patanjali to raise Rs 250 crore through debentures

    ED takes action against bootleggers, attach assets in Indore

    ED takes action against bootleggers, attach assets in Indore

    Flight services at WB’s Bagdogra airport to resume from tomorrow

    Flight services at WB’s Bagdogra airport to resume from tomorrow

  • Economy

    India’s animal spirits stabilize as virus rages across economy

    The Latest: Trump sees economy rebound by Election Day | Govt-and-politics

    NYC economy & small business series coming to amRUSH next week

    NYC economy & small business series coming to amRUSH next week

    Cramer says the stock market too optimistic about economic recovery

    Cramer says the stock market too optimistic about economic recovery

    The Texas economy is slowly reopening, but our electricity use isn’t showing it

    The Texas economy is slowly reopening, but our electricity use isn’t showing it

    Derby’s Take: New Data Suggests the Economy May Have Seen the Worst of It

    Derby’s Take: New Data Suggests the Economy May Have Seen the Worst of It

    Coronavirus latest: French economy to shrink more than 8% in 2020

    Coronavirus latest: French economy to shrink more than 8% in 2020

    Coronavirus has made digital taxes an even bigger threat to US economy

    Coronavirus has made digital taxes an even bigger threat to US economy

    Stock futures continue rally as economic activity resumes

    Stock futures continue rally as economic activity resumes

  • Technology

    Use of technology, integration yielded top spot for State police: DGP

    Apple Hits Record After December Surge Sends It Past Amazon

    JioPhone 3: What we know about Google – Jio partnered phone

    Airtel says no broadband outage after users reported issues

    Airtel says no broadband outage after users reported issues

    PUBG Mobile Fourex map now available in latest beta for Android, iOS: Report

    PUBG Mobile Fourex map now available in latest beta for Android, iOS: Report

    SpaceX ready for defining moment with first humans on rocket

    SpaceX ready to launch NASA astronauts, back on home turf

    Google faces antitrust case in India over payments app – sources

    Google faces antitrust case in India over payments app – sources

    Google Pay’s ‘Nearby Spot’ now available in 35 Indian cities

    Google Pay’s ‘Nearby Spot’ now available in 35 Indian cities

    Sari Baldauf Takes Over as Nokia Chair From Siilasmaa | Technology News

    Sari Baldauf Takes Over as Nokia Chair From Siilasmaa | Technology News

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Experts see progress in Oxford’s Covid vaccine

by mynews
May 15, 2020
in Science
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Experts see progress in Oxford’s Covid vaccine
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The scientists at Oxford University’s Jenner Institute, who are developing a vaccine for the novel coronavirus have passed an important hurdle. First results of a recent animal trial of the promising coronavirus vaccine from Oxford University were posted on Wednesday.

The pre-print results showed that the “ChAdOx1 nCoV-19” vaccine has been effective in preventing damage to the lungs without any signs of immune-enhanced diseases. Six monkeys were infected with a high dose of SARS-CoV-2, the virus which causes the Covid-19. As on May 13, more than 1000 volunteers have already participated in human clinical trails of this vaccine.

Independent experts have lauded the results and noted that even though the human clinical trials are already in progress, the results of this study is good news.

“The most important finding to me is the combination of considerable efficacy in terms of viral load and subsequent pneumonia, but no evidence of immune-enhanced disease, which has been a concern for vaccines in general, for example with vaccines against respiratory syncytial virus (RSV), and for SARS vaccines,” Prof Stephen Evans, Professor of Pharmacoepidemiology, London School of Hygiene and Tropical Medicine, said.

Experts believe that one of the biggest challenges with vaccines against the coronavirus species is the “potential for antibody-dependent enhancement of the disease”, which has been one reason for the lack of a vaccine against the 2003 SARS CoV strain.

“It is helpful to see that monkeys vaccinated with this SARS CoV2 vaccine did not have any evidence of enhanced lung pathology and that, despite some evidence of upper respiratory tract infection by SARS COV2 after high viral load virus challenge, monkeys given the vaccine did not have any evidence of pneumonia,” Dr Penny Ward, Visiting Professor in Pharmaceutical Medicine at King’s College London said.

Even though more than 1000 people have participated in the human trials of this vaccine, the controlled animal trials are being conducted in US and UK because it let’s researchers infect the subjects with the virus and see if the vaccine works and if there are any signs of side effects.

Asked if the results of controlled animal trails would necessarily translate into results of human trials, Prof Evans said: “No we don’t know for sure, that’s why trials need to be, and are being, done in humans, but it is encouraging to see these results and suggests cautious optimism for the Oxford vaccine trial being done in humans.”

On the other hand, a negative result in the study could have produced hurdles in the further human trials of the vaccine but scientists are now hopeful about phase 3 of human clinical trials. “These results support the ongoing clinical trial of the vaccine in humans, the results of which are eagerly awaited” added Dr Ward.

The development of the vaccine is being led by Sarah Gilbert, who is Professor of Vaccinology at the University of Oxford and leads the Jenner Institute programme on new vaccines against influenza. The group has tied up with several vaccine manufacturing firms including the Pune based Serum Institute of India for mass production of the Covid vaccine.

IndiaToday.in has plenty of useful resources that can help you better understand the coronavirus pandemic and protect yourself. Read our comprehensive guide (with information on how the virus spreads, precautions and symptoms), watch an expert debunk myths, and access our dedicated coronavirus page.

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